The Purgo Pouch is a preclinical combination product, with clinical testing planned in 2026. Statements made are based on preclinical studies, which have been conducted in over 140 sheep.

How The Purgo Pouch Technology Works

Purgo Scientific Logo

Surgical Site Infection

By the Numbers in the U.S.

Surgical Site Infections Cost the U.S. Healthcare System

$10 BILLION ANNUALLY

And Impact Over 300,000 Patients a Year

#1

Cause of Healthcare Acquired Infections

9,000

Number of U.S. Patients that Die From SSI Annually

#1

Cause of Readmissions After Surgery

9.7

Average Number of Days in Hospital Due to SSI

Surgical Site Infection

By the Numbers in the U.S.

Surgical Site Infections Cost the U.S. Healthcare System

$10 BILLION ANNUALLY

And Impact Over 300,000 Patients a Year

#1

Cause of Healthcare Acquired Infections

9,000

Number of U.S. Patients that Die From SSI Annually

#1

Cause of Readmissions After Surgery

9.7

Average Number of Days in Hospital Due to SSI

Surgical Site Infection

By the Numbers in the U.S.

Surgical Site Infections Cost the U.S. Healthcare System

$10 BILLION ANNUALLY

And Impact Over 300,000 Patients a Year

#1

Cause of Healthcare Acquired Infections

9,000

Number of U.S. Patients that Die From SSI Annually

#1

Cause of Readmissions After Surgery

9.7

Average Number of Days in Hospital Due to SSI

Causes Of Infection

Planktonic vs Biofilm

Biofilms can severely complicate infection.
What Are Planktonic Bacteria?

What Are Planktonic Bacteria?

  • Individual bacteria.
  • Float in a liquid medium like blood.
  • Metabolically active.
  • More susceptible to antibiotics.
  • Readily controlled by host immune cells.
What Are Bacterial Biofilms?

What Are Bacterial Biofilms?

  • Communities of bacteria.
  • Primarily attach to solid surfaces.
  • Metabolically inactive.
  • Less susceptible to antibiotics.
  • Can cause recurring infections.
What are Planktonic Bacteria?

What are Planktonic Bacteria?

  • Individual bacteria.
  • Float in a liquid medium like blood.
  • Metabolically active.
  • More susceptible to antibiotics.
  • Readily controlled by host immune cells.
What are Bacterial Biofilms?

What are Bacterial Biofilms?

  • Communities of bacteria.
  • Primarily attach to solid surfaces.
  • Metabolically inactive.
  • Less susceptible to antibiotics.
  • Can cause recurring infections.
What are Planktonic Bacteria?

What are Planktonic Bacteria?

  • Individual bacteria.
  • Float in a liquid medium like blood.
  • Metabolically active.
  • More susceptible to antibiotics.
  • Readily controlled by host immune cells.
What are Bacterial Biofilms?

What are Bacterial Biofilms?

  • Communities of bacteria.
  • Primarily attach to solid surfaces.
  • Metabolically inactive.
  • Less susceptible to antibiotics.
  • Can cause recurring infections.

The Solution

The Right Therapy

Purgo Pouch will deliver an effective tobramycin dose to kill biofilms.

The Right Place

Purgo Pouch targets infection by delivering tobramycin locally in the surgical wound site.

The Right Duration

Purgo Pouch sustains tobramycin delivery for up to 30 days, offering unparallelled versatility.

The Solution

The Right Therapy

Purgo Pouch will deliver an effective tobramycin dose to kill biofilms.

The Right Place

Purgo Pouch targets infection by delivering tobramycin locally in the surgical wound site.

The Right Duration

Purgo Pouch sustains tobramycin delivery for up to 30 days, offering unparallelled versatility.

Kirt Kimball, MD

Purgo Pouch is a breakthrough medical device that will deliver controlled local antibiotics. The promise of controlled local drug delivery without systemic side effects and toxicity is transformative for the treatment and prevention of deep infection. I look forward to using it in my practice.

International College of Surgeons

“Surgical site infection is disastrous in orthopedic practice as it is difficult to rid the bone and joint of the infection.” Prevalence of Surgical Site Infection in Orthopedic Surgery: A 5-year Analysis – June 2014, International Surgery – Official Journal of the International College of Surgeons

Adam Hadhazy

“When encased in biofilms in the human body, bacteria are a thousand times less susceptible to antibiotics."

Edmiston C.E., McBain A.J., Roberts C., Leaper

"The global impact of surgical site infections is monumental and as many as 80% of these infections may involve a microbial biofilm.” Edmiston C.E., McBain A.J., Roberts C., Leaper D. (2015) Clinical and Microbiological Aspects of Biofilm-Associated Surgical Site Infections. In: Donelli G. (eds) Biofilm-based Healthcare-associated Infections. Advances in Experimental Medicine and Biology, vol 830. Springer, Cham. doi.org/10.1007/978-3-319-11038-

David L. Rotherberg, MD

The Purgo Pouch stands as a groundbreaking tool in localized antibiotic delivery, addressing deep infection treatment, prevention, and advancing the current surgical infection management. This level of control over drug delivery is a game-changer, and I am excited to see its impact in my clinical work.

Jeremy Shaw, MD

The Purgo Pouch is a breakthrough medical device that will deliver controlled local antibiotics. The promise of controlled local drug delivery without systemic side effects and toxicity is tranformative for the treatment and prevention of deep infection. I look forward to using it in my practice.

Purgo Pouch Is Superior To Current Clinical Approaches

SSI Treatment Options

Purgo Pouch Sustained Delivery Device*

Oral Antibiotic Administration

IV Antibiotic Administration

Antibiotic-Impregnated Beads

Local Antibiotic Powder or Lavage Application

Effective Planktonic Bacterial Control

Dot
Dot
Dot
Dot
Dot

Flexibility to Change Antibiotics

Dot
Dot
Dot

Continuous Daily Therapy

Dot
Dot

Effective Biofilm Eradication

Dot

*As shown in preclinical studies

Purgo Pouch Is Superior To Current Clinical Approaches

SSI Treatment Options

Purgo Pouch Sustained Delivery Device*

Effective Planktonic Bacterial Control

Flexibility to Change Antibiotics

Continuous Daily Therapy

Effective Biofilm Eradication

Oral Antibiotic Administration

Effective Planktonic Bacteria Control

Flexibility to Change Antibiotics

Continuous Daily Therapy

Effective Biofilm Eradication

IV Antibiotic Administration

Effective Planktonic Bacteria Control

Flexibility to Change Antibiotics

Continuous Daily Therapy

Effective Biofilm Eradication

Antibiotic-Impregnated Beads

Effective Planktonic Bacteria Control

Flexibility to Change Antibiotics

Continuous Daily Therapy

Effective Biofilm Eradication

Local Antibiotic Powder or Lavage Application

Effective Planktonic Bacteria Control

Flexibility to Change Antibiotics

Continuous Daily Therapy

Effective Biofilm Eradication

*As shown in preclinical studies

Home