Purgo's Technology
Purgo Pouch consists of a rate-controlled membrane that allows for passive diffusion of therapeutic over a concentration gradient, no pumps or batteries required.
The Challenge: Surgical Site Infections
By the Numbers in the U.S.
Surgical Site Infections Cost the U.S. Healthcare System
$10 BILLION ANNUALLY
And Impact Over 300,000 Patients a Year
#1
Cause of Healthcare Acquired Infections
9,000
Number of U.S. Patients that Die From SSI Annually
#1
Cause of Readmissions After Surgery
9.7
Average Number of Days in Hospital Due to SSI
Surgical Site Infection
By the Numbers in the U.S.
Surgical Site Infections Cost the U.S. Healthcare System
$10 BILLION ANNUALLY
And Impact Over 300,000 Patients a Year
#1
Cause of Healthcare Acquired Infections
9,000
Number of U.S. Patients that Die From SSI Annually
#1
Cause of Readmissions After Surgery
9.7
Average Number of Days in Hospital Due to SSI
Causes Of Infection
Planktonic vs Biofilm
What Are Planktonic Bacteria?
- Individual bacteria.
- Float in a liquid medium like blood.
- Metabolically active.
- More susceptible to antibiotics.
- Readily controlled by host immune cells.
What Are Bacterial Biofilms?
- Communities of bacteria.
- Primarily attach to solid surfaces.
- Metabolically inactive.
- Less susceptible to antibiotics.
- Can cause recurring infections.
What are Planktonic Bacteria?
- Individual bacteria.
- Float in a liquid medium like blood.
- Metabolically active.
- More susceptible to antibiotics.
- Readily controlled by host immune cells.
What are Bacterial Biofilms?
- Communities of bacteria.
- Primarily attach to solid surfaces.
- Metabolically inactive.
- Less susceptible to antibiotics.
- Can cause recurring infections.
The Solution: Purgo Pouch
The Right Therapy
Purgo Pouch will deliver an effective antibiotic dose to kill biofilms.
The Right Place
Purgo Pouch targets infection by delivering antibiotic locally in the surgical wound site.
The Right Duration
Purgo Pouch sustains antibiotic delivery for up to 30 days, offering unparallelled versatility.
The Solution
The Right Therapy
Purgo Pouch will deliver an effective tobramycin dose to kill biofilms.
The Right Place
Purgo Pouch targets infection by delivering tobramycin locally in the surgical wound site.
The Right Duration
Purgo Pouch sustains tobramycin delivery for up to 30 days, offering unparallelled versatility.
Purgo Pouch Is Superior To Current Clinical Approaches
SSI Treatment Options
Purgo Pouch Sustained Delivery Device*
Oral Antibiotic Administration
IV Antibiotic Administration
Antibiotic-Impregnated Beads
Local Antibiotic Powder or Lavage Application
Effective Planktonic Bacterial Control
Flexibility to Change Antibiotics
Continuous Daily Therapy
Effective Biofilm Eradication
*As shown in preclinical studies